ZNF132

Across TCGA patient cohorts, ZNF132 mutation is significantly associated with the RNA expression of many other genes, with 3,419 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF132-associated genes across cancer lineages are ENO1, MCM5, and TNNC2. Each is linked with ZNF132 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF132-to-partner and partner-to-ZNF132 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ENO1 grouped by ZNF132-low versus ZNF132-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF132→partner) and Y-score (partner→ZNF132) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ENO1 →	+0.552	+4.021	<.001	<.001	3	3
UCEC	MCM5 →	+0.661	+2.010	<.001	<.001	3	3
UCEC	TNNC2 →	-0.623	-1.925	.006	.004	3	3
READ	RNU6-1274P →	+0.547	+5.925	<.001	.002	3	2
UCEC	PLBD2 →	+0.397	+1.551	<.001	.002	3	2
UCEC	SLC25A4 →	+0.500	+2.010	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,419 associations by consensus.

ENO1 by ZNF132 expression — UCEC

Explore this box plot interactively →