ZNF131

Across TCGA pan-cancer cohorts, ZNF131 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF131 data layer compared with 24 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZNF131 Mutation is associated with better overall survival. In most high-consensus cancer types, elevated ZNF131 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, LUSC, and ESCA are the cancer types where ZNF131 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.659	.017	28	view →
LUSC	OS	Median	II,III,IV	0.139	0.745	<.001	18	view →
ESCA	OS	Median	All	0.080	0.701	<.001	12	view →
ACC	OS	Median	All	0.273	0.818	.031	9	view →
STAD	OS	Median	III,IV	0.501	0.629	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZNF131–UCEC (OS)

Open the UCEC breakdown →