ZNF131

Across TCGA pan-cancer cohorts, ZNF131 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ZNF131 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ZNF131 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF131 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

PDAC, UCEC, and CCRCC are the cancer types where ZNF131 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.222	0.695	.002	20	view →
UCEC	OS	Quartile	III,IV	0.288	1.000	.018	8	view →
CCRCC	OS	Tertile	All	1.000	0.629	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ZNF131–PDAC (OS)

Open the PDAC breakdown →