ZNF131

Across TCGA patient cohorts, ZNF131 mutation is significantly associated with the RNA expression of many other genes, with 1,828 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF131-associated genes across cancer lineages are MIR6803, RNU6-338P, and ZNF90P3. Each is linked with ZNF131 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF131-to-partner and partner-to-ZNF131 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by ZNF131-low versus ZNF131-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF131→partner) and Y-score (partner→ZNF131) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.079	+3.834	<.001	.007	3	3
BRCA	RNU6-338P →	+0.161	+4.201	<.001	.007	3	2
BLCA	ZNF90P3 →	+0.036	+4.177	<.001	.002	3	2
BLCA	TSPY11P →	+0.047	+4.814	<.001	.003	3	2
LUSC	MIR502 →	+0.370	+6.593	<.001	<.001	3	2
LUAD	RNA5SP38 →	+0.283	+3.629	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,828 associations by consensus.

MIR6803 by ZNF131 expression — UCEC

Explore this box plot interactively →