ZNF131

Across TCGA cell cohorts, ZNF131 mutation is significantly associated with the RNA expression of many other genes, with 320 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF131-associated genes across cancer lineages are F9, ZIC3, and DEFB4A. Each is linked with ZNF131 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF131-to-partner and partner-to-ZNF131 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, F9 grouped by ZNF131-low versus ZNF131-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF131→partner) and Y-score (partner→ZNF131) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	F9 →	+0.014	+4.969	<.001	.003	3	1
BLOOD_Leukemia	ZIC3 →	+0.019	+5.060	<.001	.001	3	1
BLOOD_Leukemia	DEFB4A →	+0.115	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	DIRC1 →	+0.037	+4.969	<.001	.003	3	1
BLOOD_Leukemia	OR5H6 →	+0.427	+4.705	<.001	.003	3	1
BLOOD_Leukemia	ASIC5 →	+0.047	+4.409	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 320 associations by consensus.

F9 by ZNF131 expression — BLOOD_Leukemia

Explore this box plot interactively →