Across TCGA patient cohorts, ZNF124 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF124-associated genes across cancer lineages are eEF2, eIF4E, and A-Raf_pS299. Each is linked with ZNF124 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF124-to-partner and partner-to-ZNF124 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF124→partner) and Y-score (partner→ZNF124) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.481	+2.700	.002	.006	3	1
UCEC	eIF4E →	+0.202	+2.183	.033	.033	3	1
UCEC	A-Raf_pS299 →	-0.181	-3.000	<.001	.036	3	1
UCEC	ERK2 →	+0.303	+2.321	<.001	.033	3	1
UCEC	FOXO3a_pS318_S321 →	-0.156	-2.700	.005	.006	3	1
UCEC	GAPDH →	+0.535	+2.999	.027	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Exploration

ZNF124 survival (RNA) · tumor vs normal (RNA) · all ZNF124 data types