Across TCGA cell cohorts, ZNF124 mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF124-associated genes across cancer lineages are TNRC6B, SH3GL2, and MAGEB4. Each is linked with ZNF124 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF124-to-partner and partner-to-ZNF124 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF124→partner) and Y-score (partner→ZNF124) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNRC6B →	+1.070	+3.064	<.001	.009	3	1
LARGE_INTESTINE	SH3GL2 →	+1.316	+3.474	<.001	.003	3	1
LARGE_INTESTINE	MAGEB4 →	+0.011	+3.415	<.001	.001	3	1
LARGE_INTESTINE	VHL →	+0.759	+3.067	.002	.009	3	1
LARGE_INTESTINE	RASGEF1C →	+0.213	+2.626	.002	.006	3	1
LARGE_INTESTINE	MSGN1 →	+0.061	+3.023	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Exploration

ZNF124 survival (RNA) · tumor vs normal (RNA) · all ZNF124 data types