Across TCGA patient cohorts, ZNF121 protein abundance is significantly associated with the RNA expression of many other genes, with 9,232 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF121-associated genes across cancer lineages are POLE2, CSNK2A1, and TMEM97. Each is linked with ZNF121 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF121-to-partner and partner-to-ZNF121 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF121→partner) and Y-score (partner→ZNF121) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	POLE2 →	+1.095	+0.552	.002	.002	3	3
LSCC	CSNK2A1 →	+0.630	+0.627	<.001	<.001	3	3
LSCC	TMEM97 →	+1.251	+0.555	<.001	<.001	3	3
GBM	PHF12 →	+0.476	+0.515	<.001	<.001	3	3
GBM	FOXM1 →	+1.332	+0.619	.003	.002	3	3
LSCC	CPSF6 →	+0.612	+0.471	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,232 associations by consensus.

Exploration

ZNF121 survival (RNA) · tumor vs normal (RNA) · all ZNF121 data types