Across TCGA cell cohorts, ZNF121 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,212 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF121-associated GO terms across cancer lineages are Subtelomeric heterochromatin formation, Protein K27-linked deubiquitination, and Regulation of body fluid levels. Each is linked with ZNF121 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF121-to-partner and partner-to-ZNF121 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF121→partner) and Y-score (partner→ZNF121) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Subtelomeric heterochromatin formation →	+0.123	+1.053	<.001	<.001	3	14
LUNG_SCLC	Protein K27-linked deubiquitination →	+0.132	+1.296	<.001	<.001	3	14
BONE	Regulation of body fluid levels →	-0.092	-1.076	<.001	<.001	2	15
SOFT_TISSUE	'de novo' AMP biosynthetic process →	+0.151	+1.186	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	DNA topological change →	+0.161	+0.961	<.001	<.001	3	13
BLOOD_Leukemia	Random inactivation of X chromosome →	+0.075	+0.828	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,212 associations by consensus.

Exploration

ZNF121 survival (RNA) · tumor vs normal (RNA) · all ZNF121 data types