ZNF12

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF12 mutation is significantly associated with the RNA expression of many other genes, with 2,984 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF12-associated genes across cancer lineages are LINC02559, NIP7P1, and UHRF1. Each is linked with ZNF12 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF12-to-partner and partner-to-ZNF12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02559 grouped by ZNF12-low versus ZNF12-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF12→partner) and Y-score (partner→ZNF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCLINC02559 →+1.025+5.342<.001.00233
BLCANIP7P1 →+0.076+4.618<.001.00533
UCECUHRF1 →+1.099+3.283<.001<.00132
UCECRNA5SP411 →+1.062+2.031<.001<.00132
HNSCRNU6-660P →+0.158+4.468.001.00632
CESCLINC02353 →+0.038+4.669<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,984 associations by consensus.

LINC02559 by ZNF12 expression — CESC

Box plot of LINC02559 in ZNF12-low vs ZNF12-high samples in CESC.

Explore this box plot interactively →

Exploration