ZNF12

Across TCGA cell cohorts, ZNF12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,279 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF12-associated GO terms across cancer lineages are Meiotic mismatch repair, Protein polyubiquitination, and Positive regulation of isotype switching to IgG isotypes. Each is linked with ZNF12 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF12-to-partner and partner-to-ZNF12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic mismatch repair grouped by ZNF12-low versus ZNF12-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF12→partner) and Y-score (partner→ZNF12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Meiotic mismatch repair →	+0.138	+0.734	<.001	<.001	3	17
PANCREAS	Protein polyubiquitination →	+0.043	+0.646	<.001	<.001	3	15
BLOOD_Lymphoma	Positive regulation of isotype switching to IgG isotypes →	+0.139	+0.843	.001	.001	2	16
SOFT_TISSUE	Protein desumoylation →	+0.096	+0.515	.002	<.001	2	12
URINARY_TRACT	Regulation of isotype switching to IgG isotypes →	+0.110	+0.600	<.001	<.001	2	12
SKIN	Regulation of translational initiation →	+0.066	+0.695	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,279 associations by consensus.

Meiotic mismatch repair by ZNF12 expression — BREAST

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