ZNF117

Across TCGA cell cohorts, ZNF117 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,909 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF117-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of myoblast fusion. Each is linked with ZNF117 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF117-to-partner and partner-to-ZNF117 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ZNF117-low versus ZNF117-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF117→partner) and Y-score (partner→ZNF117) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of myoblast fusion →	+0.101	+1.678	<.001	<.001	3	13
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.100	+1.678	<.001	<.001	3	13
OVARY	Regulation of myoblast fusion →	+0.092	+1.000	<.001	<.001	3	13
LUNG_SCLC	Positive regulation of double-strand break repair →	+0.079	+1.680	<.001	<.001	3	13
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.097	+1.651	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Stress granule assembly →	+0.139	+1.448	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,909 associations by consensus.

Negative regulation of myoblast fusion by ZNF117 expression — OVARY

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