Across TCGA patient cohorts, ZNF107 mutation is significantly associated with the total protein of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF107-associated genes across cancer lineages are Rab25, 4E-BP1_pT70, and 14-3-3_beta. Each is linked with ZNF107 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF107-to-partner and partner-to-ZNF107 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF107→partner) and Y-score (partner→ZNF107) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rab25 →	-0.261	-2.807	.006	.002	3	3
COAD	4E-BP1_pT70 →	+0.134	+3.467	.013	.002	3	3
UCEC	14-3-3_beta →	-0.080	-1.156	.005	.017	3	2
UCEC	EGFR_pY1068 →	-0.213	-1.938	.003	.001	3	2
UCEC	A-Raf_pS299 →	-0.111	-1.807	.001	.003	3	2
UCEC	Gab2 →	+0.215	+1.502	.036	.027	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

Exploration

ZNF107 survival (RNA) · tumor vs normal (RNA) · all ZNF107 data types