ZNF106

Across TCGA cell cohorts, ZNF106 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,644 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF106-associated GO terms across cancer lineages are Phosphatidylinositol biosynthetic process, Epigenetic regulation of gene expression, and Cytosolic transport. Each is linked with ZNF106 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF106-to-partner and partner-to-ZNF106 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol biosynthetic process grouped by ZNF106-low versus ZNF106-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF106→partner) and Y-score (partner→ZNF106) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol biosynthetic process →	+0.072	+1.146	<.001	<.001	3	16
SOFT_TISSUE	Epigenetic regulation of gene expression →	+0.060	+1.631	<.001	<.001	3	16
LARGE_INTESTINE	Cytosolic transport →	+0.058	+0.904	.001	<.001	3	15
SOFT_TISSUE	Negative regulation of chromosome condensation →	+0.211	+1.948	<.001	<.001	3	15
BONE	Regulation of hippo signaling →	+0.091	+0.797	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.122	+1.251	.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,644 associations by consensus.

Phosphatidylinositol biosynthetic process by ZNF106 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →