ZNF106

Across TCGA cell cohorts, ZNF106 mutation is significantly associated with the RNA expression of many other genes, with 1,421 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF106-associated genes across cancer lineages are CCDC110, PRR30, and MAGEB10. Each is linked with ZNF106 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF106-to-partner and partner-to-ZNF106 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC110 grouped by ZNF106-low versus ZNF106-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF106→partner) and Y-score (partner→ZNF106) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CCDC110 →	+0.450	+3.449	.005	.003	3	2
BLOOD_Leukemia	PRR30 →	+0.011	+3.362	<.001	.001	3	2
BLOOD_Lymphoma	MAGEB10 →	+0.077	+3.342	<.001	.008	3	2
BLOOD_Lymphoma	ZNF729 →	+0.381	+4.209	<.001	.001	3	2
BLOOD_Lymphoma	FAM24A →	+0.036	+4.247	<.001	.004	3	2
BLOOD_Lymphoma	TP53TG3D →	+1.746	+3.781	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,421 associations by consensus.

CCDC110 by ZNF106 expression — BLOOD_Leukemia

Explore this box plot interactively →