ZNF100

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF100 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF100-associated genes across cancer lineages are mTOR_pS2448, Notch1, and p62 Lck ligand. Each is linked with ZNF100 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF100-to-partner and partner-to-ZNF100 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF100→partner) and Y-score (partner→ZNF100) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECmTOR_pS2448 →-0.111-1.643.015.01032
UCECNotch1 →+0.158+2.515<.001<.00132
UCECp62 Lck ligand →+0.376+3.087<.001<.00132
UCECPCNA →+0.191+2.906.003.00132
UCECRictor_pT1135 →-0.071-1.473.023.00632
UCECShc_pY317 →-0.127-1.874.006.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration