Across TCGA cell cohorts, ZNF100 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF100-associated genes across cancer lineages are SCGB1D2, PRAMEF33, and TBL1Y. Each is linked with ZNF100 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF100-to-partner and partner-to-ZNF100 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF100→partner) and Y-score (partner→ZNF100) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SCGB1D2 →	+2.330	+3.206	<.001	.008	3	1
LUNG_SCLC	PRAMEF33 →	+0.245	+3.292	.002	.002	3	1
LUNG_SCLC	TBL1Y →	+0.419	+2.866	.002	.008	3	1
UPPER_AERODIGESTIVE_TRACT	OR9A2 →	+0.025	+4.510	<.001	.003	3	1
UPPER_AERODIGESTIVE_TRACT	IQCF5 →	+0.042	+4.357	<.001	.006	3	1
LARGE_INTESTINE	IL20 →	+0.202	+3.662	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

ZNF100 survival (RNA) · tumor vs normal (RNA) · all ZNF100 data types