ZNF10

Across TCGA pan-cancer cohorts, ZNF10 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ZNF10 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ZNF10 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF10 expression acts as an unfavorable survival marker.

BLCA, UCEC, and HNSC are the cancer types where ZNF10 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	IV	0.238	0.602	.024	9	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
HNSC	DFS	Median	II,III,IV	0.321	0.698	.016	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ZNF10–BLCA (OS)

Open the BLCA breakdown →