ZNF10

Across TCGA patient cohorts, ZNF10 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF10-associated genes across cancer lineages are TAZ, ASNS, and FASN. Each is linked with ZNF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF10-to-partner and partner-to-ZNF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAZ grouped by ZNF10-low versus ZNF10-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF10→partner) and Y-score (partner→ZNF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TAZ →	+0.234	+2.832	.030	.034	3	2
COAD	ASNS →	+0.686	+2.815	.001	.036	3	2
COAD	FASN →	+0.431	+2.815	.045	.036	3	1
COAD	Notch1 →	+0.338	+2.815	<.001	.036	2	2
COAD	PTEN →	+0.193	+2.815	.012	.036	3	1
UCEC	EGFR →	-0.187	-1.807	.004	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

TAZ by ZNF10 expression — COAD

Explore this box plot interactively →