ZNF10

Across TCGA cell cohorts, ZNF10 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZNF10-associated genes across cancer lineages are LY6L, LHCGR, and OR10V1. Each is linked with ZNF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF10-to-partner and partner-to-ZNF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LY6L grouped by ZNF10-low versus ZNF10-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF10→partner) and Y-score (partner→ZNF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	LY6L →	+0.020	+4.906	<.001	.006	3	1
LARGE_INTESTINE	LHCGR →	+0.050	+4.467	<.001	.004	3	1
SKIN	OR10V1 →	+0.016	+4.437	<.001	.004	3	1
SKIN	SUPT20HL1 →	+0.021	+4.054	<.001	.004	3	1
SKIN	GOLGA6L22 →	+0.004	+4.437	<.001	.004	3	1
SKIN	TLR8 →	+0.013	+4.614	<.001	.004	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

LY6L by ZNF10 expression — OESOPHAGUS

Explore this box plot interactively →