ZMYND12

Across TCGA patient cohorts, ZMYND12 mutation is significantly associated with the RNA expression of many other genes, with 1,136 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMYND12-associated genes across cancer lineages are RNA5SP519, OR1D4, and MIR548D2. Each is linked with ZMYND12 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZMYND12-to-partner and partner-to-ZMYND12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP519 grouped by ZMYND12-low versus ZMYND12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYND12→partner) and Y-score (partner→ZMYND12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP519 →	+0.466	+2.304	<.001	.005	3	3
BRCA	OR1D4 →	+0.039	+5.800	.003	.003	3	2
BRCA	MIR548D2 →	+0.437	+6.950	<.001	<.001	3	2
UCEC	MIR3661 →	+0.790	+2.256	<.001	<.001	3	2
STAD	MIR521-2 →	+0.671	+4.480	.001	.005	3	2
STAD	RNA5SP24 →	+0.754	+4.480	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,136 associations by consensus.

RNA5SP519 by ZMYND12 expression — UCEC

Explore this box plot interactively →