ZMYND12

Across TCGA cell cohorts, ZMYND12 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZMYND12-associated genes across cancer lineages are TGIF2LY, SCGB1C1, and G6PC2. Each is linked with ZMYND12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYND12-to-partner and partner-to-ZMYND12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TGIF2LY grouped by ZMYND12-low versus ZMYND12-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYND12→partner) and Y-score (partner→ZMYND12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	TGIF2LY →	+0.026	+5.169	<.001	.005	3	1
BREAST	SCGB1C1 →	+0.074	+5.169	<.001	.005	3	1
LARGE_INTESTINE	G6PC2 →	+0.050	+3.777	<.001	.007	3	1
LARGE_INTESTINE	FAM205A →	+0.023	+3.614	<.001	.006	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TGIF2LY by ZMYND12 expression — BREAST

Explore this box plot interactively →