ZMYND11

Across TCGA patient cohorts, ZMYND11 mutation is significantly associated with the RNA expression of many other genes, with 3,009 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMYND11-associated genes across cancer lineages are RNU4-64P, RPS6P20, and LINC01607. Each is linked with ZMYND11 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZMYND11-to-partner and partner-to-ZMYND11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-64P grouped by ZMYND11-low versus ZMYND11-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYND11→partner) and Y-score (partner→ZMYND11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU4-64P →	+0.175	+4.327	.005	.009	3	3
HNSC	RPS6P20 →	+0.198	+3.921	<.001	.007	3	3
UCEC	LINC01607 →	-0.514	-2.226	<.001	.001	3	2
UCEC	ZNF280B →	+0.530	+1.541	<.001	.002	3	2
UCEC	CCL4 →	+0.801	+2.021	<.001	<.001	3	2
UCEC	TADA2A →	+0.284	+1.912	.006	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,009 associations by consensus.

RNU4-64P by ZMYND11 expression — HNSC

Explore this box plot interactively →