ZMYND11

Across TCGA cell cohorts, ZMYND11 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZMYND11-associated genes across cancer lineages are KRT25, OOSP4B, and IZUMO1R. Each is linked with ZMYND11 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYND11-to-partner and partner-to-ZMYND11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT25 grouped by ZMYND11-low versus ZMYND11-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYND11→partner) and Y-score (partner→ZMYND11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	KRT25 →	+0.063	+4.421	<.001	.004	3	1
BREAST	OOSP4B →	+0.030	+4.781	<.001	.003	3	1
UPPER_AERODIGESTIVE_TRACT	IZUMO1R →	+0.053	+4.736	<.001	.009	3	1
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1
LARGE_INTESTINE	CHIA →	+0.041	+3.345	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

KRT25 by ZMYND11 expression — BREAST

Explore this box plot interactively →