ZMYND10

Across TCGA patient cohorts, ZMYND10 mutation is significantly associated with the RNA expression of many other genes, with 1,617 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMYND10-associated genes across cancer lineages are RNU6-374P, SNORD116-23, and RN7SKP286. Each is linked with ZMYND10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYND10-to-partner and partner-to-ZMYND10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-374P grouped by ZMYND10-low versus ZMYND10-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYND10→partner) and Y-score (partner→ZMYND10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-374P →	+0.106	+7.473	<.001	.007	3	2
BRCA	SNORD116-23 →	+0.436	+4.924	.005	.002	3	2
UCEC	RN7SKP286 →	+0.042	+3.890	<.001	.007	3	2
BRCA	MIR6894 →	+0.395	+4.506	<.001	.009	3	1
BRCA	RN7SL460P →	+0.157	+5.760	<.001	<.001	3	1
CESC	VDAC2P4 →	+0.086	+5.010	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,617 associations by consensus.

RNU6-374P by ZMYND10 expression — BRCA

Explore this box plot interactively →