ZMYM5

Across TCGA patient cohorts, ZMYM5 mutation is significantly associated with the RNA expression of many other genes, with 4,679 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMYM5-associated genes across cancer lineages are IGHD3-16, RNA5SP222, and USP9YP2. Each is linked with ZMYM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYM5-to-partner and partner-to-ZMYM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHD3-16 grouped by ZMYM5-low versus ZMYM5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM5→partner) and Y-score (partner→ZMYM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGHD3-16 →	+0.923	+1.996	<.001	<.001	3	2
UCEC	RNA5SP222 →	+0.153	+2.761	<.001	.009	3	2
UCEC	USP9YP2 →	+0.011	+4.311	<.001	.002	3	2
SKCM	MIR3619 →	+0.463	+4.765	<.001	.003	3	2
BRCA	RNU6-116P →	+0.327	+6.027	<.001	<.001	3	2
BLCA	RPS10P21 →	+0.181	+4.417	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,679 associations by consensus.

IGHD3-16 by ZMYM5 expression — UCEC

Explore this box plot interactively →