ZMYM5

Across TCGA cell cohorts, ZMYM5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,005 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZMYM5-associated GO terms across cancer lineages are Negative regulation of hematopoietic stem cell differentiation, Endoplasmic reticulum mannose trimming, and Protein desumoylation. Each is linked with ZMYM5 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZMYM5-to-partner and partner-to-ZMYM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of hematopoietic stem cell differentiation grouped by ZMYM5-low versus ZMYM5-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM5→partner) and Y-score (partner→ZMYM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of hematopoietic stem cell differentiation →	+0.166	+1.412	<.001	<.001	3	13
STOMACH	Endoplasmic reticulum mannose trimming →	+0.103	+0.800	<.001	.006	3	12
LUNG_SCLC	Protein desumoylation →	+0.081	+0.585	.001	<.001	3	11
OESOPHAGUS	Protein demannosylation →	+0.121	+0.799	<.001	.009	2	12
OESOPHAGUS	Protein alpha-1,2-demannosylation →	+0.121	+0.799	<.001	.009	2	12
OESOPHAGUS	Protein deglycosylation →	+0.125	+0.801	.001	.009	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,005 associations by consensus.

Negative regulation of hematopoietic stem cell differentiation by ZMYM5 expression — BLOOD_Myeloma

Explore this box plot interactively →