ZMYM5

Across TCGA cell cohorts, ZMYM5 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZMYM5-associated genes across cancer lineages are ATP6V1G3, OR9K2, and ADIG. Each is linked with ZMYM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYM5-to-partner and partner-to-ZMYM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP6V1G3 grouped by ZMYM5-low versus ZMYM5-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM5→partner) and Y-score (partner→ZMYM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ATP6V1G3 →	+0.297	+3.700	<.001	.008	3	1
PANCREAS	OR9K2 →	+0.008	+4.029	<.001	.007	3	1
PANCREAS	ADIG →	+0.034	+4.029	<.001	.007	3	1
BLOOD_Lymphoma	ARMC3 →	+0.115	+3.754	.001	.008	3	1
BLOOD_Lymphoma	ANKRD33 →	+0.003	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	TRIM49B →	+0.319	+3.714	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

ATP6V1G3 by ZMYM5 expression — PANCREAS

Explore this box plot interactively →