ZMYM4

Across TCGA patient cohorts, ZMYM4 mutation is significantly associated with the RNA expression of many other genes, with 6,264 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMYM4-associated genes across cancer lineages are MIR3661, NUDT19P5, and MRPS15. Each is linked with ZMYM4 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZMYM4-to-partner and partner-to-ZMYM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3661 grouped by ZMYM4-low versus ZMYM4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM4→partner) and Y-score (partner→ZMYM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3661 →	+0.542	+1.345	<.001	<.001	3	3
HNSC	NUDT19P5 →	+0.194	+4.295	<.001	.008	3	3
UCEC	MRPS15 →	+0.330	+1.530	<.001	<.001	3	3
BLCA	MIR34AHG →	+0.470	+3.234	.003	.008	3	3
SCLC	OR51M1 →	+0.076	+5.189	.004	.006	3	2
CESC	RN7SKP25 →	+0.351	+4.364	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,264 associations by consensus.

MIR3661 by ZMYM4 expression — UCEC

Explore this box plot interactively →