ZMYM3

Across TCGA cell cohorts, ZMYM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,720 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZMYM3-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Heterochromatin formation, and Regulation of transcription initiation by RNA polymerase II. Each is linked with ZMYM3 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZMYM3-to-partner and partner-to-ZMYM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by ZMYM3-low versus ZMYM3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM3→partner) and Y-score (partner→ZMYM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.174	+0.976	<.001	<.001	3	18
STOMACH	Heterochromatin formation →	+0.100	+1.369	<.001	<.001	3	17
LUNG_SCLC	Regulation of transcription initiation by RNA polymerase II →	+0.070	+0.589	<.001	.008	3	17
STOMACH	Constitutive heterochromatin formation →	+0.142	+1.389	<.001	<.001	3	16
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.145	+0.979	<.001	<.001	3	16
BONE	Epigenetic regulation of gene expression →	+0.096	+1.265	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,720 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by ZMYM3 expression — URINARY_TRACT

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