ZMYM3

Across TCGA cell cohorts, ZMYM3 mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZMYM3-associated genes across cancer lineages are SNTG2, SPACA1, and PGK2. Each is linked with ZMYM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYM3-to-partner and partner-to-ZMYM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNTG2 grouped by ZMYM3-low versus ZMYM3-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM3→partner) and Y-score (partner→ZMYM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	SNTG2 →	+0.077	+3.129	.009	.007	3	2
SOFT_TISSUE	SPACA1 →	+0.023	+5.977	<.001	.001	3	1
SOFT_TISSUE	PGK2 →	+0.209	+4.930	<.001	.008	3	1
LUNG_NSCLC_LUAD	SSX7 →	+0.022	+5.662	<.001	.002	3	1
OVARY	OR10C1 →	+0.003	+3.807	<.001	.009	3	1
SKIN	KCTD8 →	+0.357	+2.956	.005	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

SNTG2 by ZMYM3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →