Across TCGA patient cohorts, ZMYM1 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMYM1-associated genes across cancer lineages are ATM, MEK1, and Notch1. Each is linked with ZMYM1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZMYM1-to-partner and partner-to-ZMYM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM1→partner) and Y-score (partner→ZMYM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.477	-1.584	.001	.009	3	3
UCEC	MEK1 →	+0.304	+1.584	.012	.009	3	2
UCEC	Notch1 →	+0.131	+1.710	.005	.025	3	2
UCEC	PCNA →	+0.200	+1.678	.005	.021	3	2
UCEC	S6_pS240_S244 →	+0.332	+2.222	.014	.010	3	2
UCEC	4E-BP1 →	+0.279	+3.584	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration

ZMYM1 survival (RNA) · tumor vs normal (RNA) · all ZMYM1 data types