ZMYM1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZMYM1 mutation is significantly associated with the RNA expression of many other genes, with 448 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZMYM1-associated genes across cancer lineages are PPIAL4A, H2BC1, and H2AC1. Each is linked with ZMYM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYM1-to-partner and partner-to-ZMYM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM1→partner) and Y-score (partner→ZMYM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEPPIAL4A →+0.047+2.544.002.00332
SOFT_TISSUEH2BC1 →+0.433+5.977<.001.00131
SOFT_TISSUEH2AC1 →+0.193+5.977<.001.00131
SOFT_TISSUEKRTAP10-1 →+0.034+5.369.002.00431
SOFT_TISSUEGAGE12E →+0.090+4.930<.001.00831
SKINCCL19 →+0.088+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 448 associations by consensus.

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