ZMIZ2

Across TCGA cell cohorts, ZMIZ2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,968 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ZMIZ2-associated GO terms across cancer lineages are 2-oxoglutarate decarboxylation to succinyl-CoA, Sperm motility, and Negative regulation of autophagy. Each is linked with ZMIZ2 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZMIZ2-to-partner and partner-to-ZMIZ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 2-oxoglutarate decarboxylation to succinyl-CoA grouped by ZMIZ2-low versus ZMIZ2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMIZ2→partner) and Y-score (partner→ZMIZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	2-oxoglutarate decarboxylation to succinyl-CoA →	+0.170	+1.347	<.001	.002	3	18
OESOPHAGUS	Sperm motility →	-0.145	-1.512	<.001	<.001	3	14
KIDNEY	Negative regulation of autophagy →	+0.074	+1.382	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.060	+1.284	<.001	<.001	3	14
SOFT_TISSUE	Cytosolic transport →	+0.066	+0.891	<.001	<.001	3	14
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.095	+0.860	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,968 associations by consensus.

2-oxoglutarate decarboxylation to succinyl-CoA by ZMIZ2 expression — OESOPHAGUS

Explore this box plot interactively →