ZMIZ1

Across TCGA cell cohorts, ZMIZ1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,487 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZMIZ1-associated GO terms across cancer lineages are Pyramidal neuron differentiation, Cerebral cortex radially oriented cell migration, and Cerebral cortex radial glia-guided migration. Each is linked with ZMIZ1 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZMIZ1-to-partner and partner-to-ZMIZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyramidal neuron differentiation grouped by ZMIZ1-low versus ZMIZ1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMIZ1→partner) and Y-score (partner→ZMIZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Pyramidal neuron differentiation →	+0.216	+1.781	<.001	<.001	3	18
LIVER	Cerebral cortex radially oriented cell migration →	+0.160	+1.486	<.001	<.001	3	16
BONE	Cerebral cortex radial glia-guided migration →	+0.165	+1.597	<.001	<.001	3	16
BONE	Telencephalon glial cell migration →	+0.165	+1.597	<.001	<.001	3	16
KIDNEY	Radial glia-guided pyramidal neuron migration →	+0.945	+1.553	.003	<.001	3	15
LUNG_SCLC	Pyramidal neuron development →	+0.178	+0.958	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,487 associations by consensus.

Pyramidal neuron differentiation by ZMIZ1 expression — BREAST

Explore this box plot interactively →