ZMAT5

Across TCGA patient cohorts, ZMAT5 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMAT5-associated genes across cancer lineages are Ku80, VEGFR2, and CD20. Each is linked with ZMAT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMAT5-to-partner and partner-to-ZMAT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by ZMAT5-low versus ZMAT5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMAT5→partner) and Y-score (partner→ZMAT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.338	+2.820	.019	.036	3	1
UCEC	VEGFR2 →	+0.443	+2.820	.015	.036	3	1
UCEC	CD20 →	+0.183	+2.827	.022	.035	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Ku80 by ZMAT5 expression — UCEC

Explore this box plot interactively →