ZMAT2

Across TCGA cell cohorts, ZMAT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,049 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZMAT2-associated GO terms across cancer lineages are Alternative mRNA splicing, via spliceosome, RNA polymerase II preinitiation complex assembly, and Regulation of transcription initiation by RNA polymerase II. Each is linked with ZMAT2 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZMAT2-to-partner and partner-to-ZMAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alternative mRNA splicing, via spliceosome grouped by ZMAT2-low versus ZMAT2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMAT2→partner) and Y-score (partner→ZMAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Alternative mRNA splicing, via spliceosome →	+0.085	+0.680	<.001	.001	3	11
LARGE_INTESTINE	RNA polymerase II preinitiation complex assembly →	+0.074	+0.651	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription initiation by RNA polymerase II →	+0.070	+0.808	<.001	<.001	3	11
LARGE_INTESTINE	Regulation of DNA-templated transcription initiation →	+0.070	+0.647	<.001	<.001	3	10
BREAST	Spliceosomal tri-snRNP complex assembly →	+0.080	+0.686	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA-templated transcription, elongation →	+0.064	+0.669	.005	.007	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,049 associations by consensus.

Alternative mRNA splicing, via spliceosome by ZMAT2 expression — SOFT_TISSUE

Explore this box plot interactively →