ZMAT2

Across TCGA cell cohorts, ZMAT2 mutation is significantly associated with the mutation status of many other genes, with 1,397 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZMAT2-associated genes across cancer lineages are ROGDI, NCBP3, and CCDC81. Each is linked with ZMAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMAT2-to-partner and partner-to-ZMAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ROGDI grouped by ZMAT2-low versus ZMAT2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMAT2→partner) and Y-score (partner→ZMAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ROGDI →	+4.087	+5.044	.001	.001	1	2
LARGE_INTESTINE	NCBP3 →	+4.087	+5.044	.001	.001	1	2
LARGE_INTESTINE	CCDC81 →	+3.672	+4.799	.002	.002	1	2
LARGE_INTESTINE	TCF7L1 →	+4.087	+5.044	.001	.001	1	2
LARGE_INTESTINE	CCDC78 →	+3.672	+4.799	.002	.002	1	2
LARGE_INTESTINE	SNX7 →	+2.865	+4.217	.007	.007	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,397 associations by consensus.

ROGDI by ZMAT2 expression — LARGE_INTESTINE

Explore this box plot interactively →