ZMAT1

Across TCGA patient cohorts, ZMAT1 mutation is significantly associated with the RNA expression of many other genes, with 3,867 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMAT1-associated genes across cancer lineages are SNORA10B, PPIH, and RGS1. Each is linked with ZMAT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZMAT1-to-partner and partner-to-ZMAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORA10B grouped by ZMAT1-low versus ZMAT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMAT1→partner) and Y-score (partner→ZMAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORA10B →	+0.142	+1.981	<.001	.002	3	3
UCEC	PPIH →	+0.308	+2.431	.003	.001	3	3
UCEC	RGS1 →	+0.683	+3.032	.004	<.001	3	3
CESC	MIR3134 →	+0.505	+4.276	.002	.008	3	3
CESC	MZT1P1 →	+0.181	+4.193	.004	.009	3	3
UCEC	SNU13 →	+0.254	+1.464	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,867 associations by consensus.

SNORA10B by ZMAT1 expression — UCEC

Explore this box plot interactively →