Across TCGA patient cohorts, ZKSCAN8 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,320 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZKSCAN8-associated proteins across cancer lineages are DEK, POGZ, and NUP153. Each is linked with ZKSCAN8 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZKSCAN8-to-partner and partner-to-ZKSCAN8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZKSCAN8→partner) and Y-score (partner→ZKSCAN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DEK →	+0.325	+0.763	<.001	<.001	3	7
GBM	POGZ →	+0.288	+0.459	<.001	<.001	3	7
LSCC	NUP153 →	+0.238	+0.523	<.001	<.001	3	6
LSCC	HDAC2 →	+0.292	+0.588	<.001	<.001	3	6
HNSC	RING1 →	+0.347	+1.016	<.001	<.001	3	6
LSCC	SPIN1 →	+0.369	+0.662	.002	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,320 associations by consensus.

Exploration

ZKSCAN8 survival (RNA) · tumor vs normal (RNA) · all ZKSCAN8 data types