Across TCGA patient cohorts, ZKSCAN8 mutation is significantly associated with the RNA expression of many other genes, with 2,007 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZKSCAN8-associated genes across cancer lineages are MIR607, CCT3P1, and OR10A7. Each is linked with ZKSCAN8 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZKSCAN8-to-partner and partner-to-ZKSCAN8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZKSCAN8→partner) and Y-score (partner→ZKSCAN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR607 →	+0.195	+4.569	<.001	.005	3	3
LUAD	CCT3P1 →	+0.088	+4.984	<.001	.005	3	3
SCLC	OR10A7 →	+0.063	+4.624	<.001	.006	3	2
LIHC	RNU6-975P →	+0.536	+5.014	<.001	.002	3	2
CESC	MIR6508 →	+0.357	+3.760	.001	.004	3	2
UCEC	PAXIP1 →	+0.331	+1.938	.009	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,007 associations by consensus.

Exploration

ZKSCAN8 survival (RNA) · tumor vs normal (RNA) · all ZKSCAN8 data types