Across TCGA patient cohorts, ZKSCAN7 mutation is significantly associated with the RNA expression of many other genes, with 3,599 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZKSCAN7-associated genes across cancer lineages are RN7SL578P, SDHA, and FMO4. Each is linked with ZKSCAN7 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZKSCAN7-to-partner and partner-to-ZKSCAN7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZKSCAN7→partner) and Y-score (partner→ZKSCAN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SL578P →	+0.164	+4.984	.001	.009	3	3
UCEC	SDHA →	+0.434	+1.584	.002	.002	3	3
UCEC	FMO4 →	-0.427	-1.842	.001	.002	3	3
BRCA	RN7SL386P →	+0.080	+4.426	<.001	.005	3	2
STAD	RBPJP2 →	+0.028	+3.109	<.001	.003	3	2
BRCA	MIR6737 →	+0.317	+3.506	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,599 associations by consensus.

Exploration

ZKSCAN7 survival (RNA) · tumor vs normal (RNA) · all ZKSCAN7 data types