Across TCGA patient cohorts, ZKSCAN7 mutation is significantly associated with the total protein of many other genes, with 47 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZKSCAN7-associated genes across cancer lineages are CDK1, GAPDH, and Notch1. Each is linked with ZKSCAN7 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZKSCAN7-to-partner and partner-to-ZKSCAN7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZKSCAN7→partner) and Y-score (partner→ZKSCAN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDK1 →	+0.352	+2.817	.006	.037	3	3
UCEC	GAPDH →	+0.356	+1.584	.041	.017	3	3
UCEC	Notch1 →	+0.164	+2.100	<.001	.002	3	3
UCEC	ASNS →	+0.288	+1.415	.014	.043	3	3
BRCA	N-Ras →	+0.244	+2.820	.021	.037	3	2
BRCA	p53 →	+0.426	+2.814	.030	.037	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Exploration

ZKSCAN7 survival (RNA) · tumor vs normal (RNA) · all ZKSCAN7 data types