ZKSCAN7-AS1

Across TCGA pan-cancer cohorts, ZKSCAN7-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ZKSCAN7-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ZKSCAN7-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZKSCAN7-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

HNSC, BRCA, and KIRP are the cancer types where ZKSCAN7-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.654	0.550	.006	77	view →
BRCA	DFS	Median	III,IV	0.874	0.712	<.001	60	view →
KIRP	DFS	Median	All	0.952	0.866	.003	55	view →
THYM	DFS	Quartile	All	1.000	0.519	.003	42	view →
KIRC	OS	Median	All	0.716	0.556	<.001	40	view →
UVM	OS	Tertile	All	0.851	0.402	.002	40	view →
CHOL	DFS	Tertile	II,III,IV	0.806	0.090	.006	35	view →
KICH	DFS	Quartile	II,III,IV	0.496	0.944	.012	28	view →
UCS	OS	Median	All	0.797	0.546	.004	24	view →
LGG	OS	Quartile	All	0.698	0.959	<.001	18	view →
READ	DFS	Median	All	0.899	0.773	.015	18	view →
GBM	OS	Quartile	All	0.538	0.324	.010	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ZKSCAN7-AS1–HNSC (DFS)

Open the HNSC breakdown →