ZKSCAN4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZKSCAN4 mutation is significantly associated with the RNA expression of many other genes, with 4,212 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZKSCAN4-associated genes across cancer lineages are MIR6508, RAD52P1, and RN7SL632P. Each is linked with ZKSCAN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZKSCAN4-to-partner and partner-to-ZKSCAN4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZKSCAN4→partner) and Y-score (partner→ZKSCAN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMIR6508 →+0.703+4.209.001.00932
SKCMRAD52P1 →+0.036+4.594<.001.00832
BRCARN7SL632P →+0.129+5.382<.001.00332
HNSCARL6IP1P1 →+0.113+5.505<.001.00432
UCECUSP9YP2 →+0.012+4.481<.001.00232
UCECRNA5SP416 →+0.629+2.306<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,212 associations by consensus.

Exploration