Across TCGA cell cohorts, ZKSCAN4 mutation is significantly associated with the drug of many other genes, with 24 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZKSCAN4-associated genes across cancer lineages are 123829, Sabutoclax, and KRAS (G12C) Inhibitor-12. Each is linked with ZKSCAN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZKSCAN4-to-partner and partner-to-ZKSCAN4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZKSCAN4→partner) and Y-score (partner→ZKSCAN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	123829 →	+0.690	+2.871	.011	.021	3	1
LARGE_INTESTINE	Sabutoclax →	+0.411	+2.991	.041	.018	3	1
LARGE_INTESTINE	KRAS (G12C) Inhibitor-12 →	+0.557	+2.868	.017	.022	3	1
LARGE_INTESTINE	KIN001-260 →	+0.446	+2.807	.012	.044	3	1
LARGE_INTESTINE	PRT062607 →	+0.680	+2.991	.003	.018	2	1
LARGE_INTESTINE	Oxaliplatin →	+0.497	+2.871	.048	.021	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

ZKSCAN4 survival (RNA) · tumor vs normal (RNA) · all ZKSCAN4 data types