Across TCGA cell cohorts, ZKSCAN3 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZKSCAN3-associated genes across cancer lineages are KRT71, VSTM2B, and C1orf141. Each is linked with ZKSCAN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZKSCAN3-to-partner and partner-to-ZKSCAN3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZKSCAN3→partner) and Y-score (partner→ZKSCAN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KRT71 →	+0.066	+4.922	<.001	.009	3	2
BREAST	VSTM2B →	+0.049	+4.672	<.001	.002	3	2
CNS	C1orf141 →	+0.012	+5.321	<.001	.005	3	1
BLOOD_Leukemia	TRIM60 →	+0.039	+5.201	<.001	.006	3	1
BLOOD_Leukemia	IQCM →	+0.031	+4.922	<.001	.009	3	1
BLOOD_Leukemia	CBLN4 →	+0.006	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

ZKSCAN3 survival (RNA) · tumor vs normal (RNA) · all ZKSCAN3 data types