ZKSCAN2

Across TCGA cell cohorts, ZKSCAN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,127 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZKSCAN2-associated GO terms across cancer lineages are Regulation of double-strand break repair, Regulation of heterochromatin organization, and Regulation of transcription initiation by RNA polymerase II. Each is linked with ZKSCAN2 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZKSCAN2-to-partner and partner-to-ZKSCAN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair grouped by ZKSCAN2-low versus ZKSCAN2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZKSCAN2→partner) and Y-score (partner→ZKSCAN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of double-strand break repair →	+0.067	+0.671	<.001	<.001	3	17
LUNG_SCLC	Regulation of heterochromatin organization →	+0.146	+0.729	.003	.002	2	17
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription initiation by RNA polymerase II →	+0.070	+0.559	<.001	.001	3	16
BONE	DNA-templated transcription initiation →	+0.095	+1.262	<.001	<.001	3	16
LUNG_SCLC	Transport along microtubule →	+0.053	+0.468	<.001	.002	3	16
BONE	Positive regulation of double-strand break repair →	+0.119	+1.297	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,127 associations by consensus.

Regulation of double-strand break repair by ZKSCAN2 expression — BREAST

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