ZKSCAN2

Across TCGA cell cohorts, ZKSCAN2 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,465 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZKSCAN2-associated GO terms across cancer lineages are Positive regulation of fibroblast proliferation, Non-proteinogenic amino acid metabolic process, and Positive regulation of focal adhesion assembly. Each is linked with ZKSCAN2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZKSCAN2-to-partner and partner-to-ZKSCAN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of fibroblast proliferation grouped by ZKSCAN2-low versus ZKSCAN2-high in BREAST.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZKSCAN2→partner) and Y-score (partner→ZKSCAN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of fibroblast proliferation →	+0.158	+1.142	<.001	<.001	3	6
OESOPHAGUS	Non-proteinogenic amino acid metabolic process →	-0.074	-0.926	.004	.008	3	5
BREAST	Positive regulation of focal adhesion assembly →	+0.147	+1.247	.007	<.001	3	5
BREAST	Positive regulation of stress fiber assembly →	+0.099	+0.997	<.001	<.001	3	5
BREAST	Regulation of SMAD protein signal transduction →	+0.045	+1.070	.004	<.001	3	5
BONE	Positive regulation of epithelial cell migration →	+0.128	+1.524	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,465 associations by consensus.

Positive regulation of fibroblast proliferation by ZKSCAN2 expression — BREAST

Explore this box plot interactively →