ZKSCAN1

Across TCGA pan-cancer cohorts, ZKSCAN1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZKSCAN1 data layer compared with 28 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ZKSCAN1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ZKSCAN1 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

COAD, CCRCC, and UCEC are the cancer types where ZKSCAN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.918	.012	30	view →
CCRCC	OS	Median	All	0.939	0.737	.003	11	view →
UCEC	OS	Median	II,III,IV	1.000	0.659	.021	8	view →
HNSC	DFS	Median	All	0.983	0.920	.008	6	view →
LUAD	OS	Median	II,III,IV	0.999	0.863	.037	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZKSCAN1–COAD (DFS)

Open the COAD breakdown →